The cast features Mehmet Bakir (Boris Trigorin), Janyce Caraballo (Irina Arkadina), Cicely Galm (Ulyana Sorin), Jacob Meyerson (Yevgeny Dorn), Zofia Ossowska ​(Yakov), Reese Parish (Nina Zarechnaya), Seoyoung Park (Polina Shamraeff), Sadie Parker (Masha Shamraeff), Fischer Vickers (Ilya Shamraeff), Onnie Williams IV (Semyon Medvedenko), and David Zavala (Constantine Trepleff).

The creative team includes lighting design by Chase Barron, original music and sound design by Ethan Korvne, costume design by Joefferry Wenderlich, wig and makeup design by Oliva Martinez, scenic design by Shokie Tseumah, stage management by Alivia Arizaga, technical direction by James Doolittle, dramaturgy by Camille Pugliese, Liz Bazzoli, and Omari Sloan, props direction by Rome Jones, intimacy direction by Toranika Washington, vocal coaching by Phil Timberlake, and disability consulting by Korey Joseph.